Ans:
依據國動(NCB)官網,外傷傷口 (Fight wounds) 常發生於 BALB/c, SJL, FVB 及 B6 公鼠,尤其容易出現在臀部及生殖道周圍,這些打鬥所造成的後遺症將造成動物急性或慢性疼痛。此外,若傷口持續性地發展將導致大範圍皮膚潰瘍、斷尾、關節炎、尾巴壞疽等慢性廣泛性炎症反應。避免大於 5 週齡雄鼠併籠、執行臨床觀察早期發現受傷的小鼠,並隔離攻擊性強的小鼠。輕度的傷口可擦拭優碘或抗生素軟膏,若已呈現嚴重的傷口 (大範圍、感染、無法癒合之傷口),應將動物進行人道犧牲。
Ans:
According to the National Center for Biomodels (NCB), fight wounds commonly occur in BALB/c, SJL, FVB, and B6 male mice, particularly the buttocks and around reproductive tract. It can cause acute or chronic pain in the animals. And persistent wounds can lead to chronic, widespread inflammatory reactions such as extensive skin ulcers, tail amputation, arthritis, and tail necrosis. Avoid combining male mice older than 5 weeks of age together. Clinical observation should be performed to identify injured mice early, and aggressive mice should be separated. Minor wounds can be treated with betadine or antibiotic ointment. Severe wounds (extensive, infected, or non-healing) should be humanely sacrificed.
